Human Resources Operations Manager

Reporting to the Head of HR, the Human Resources Operations Manager will help elevate our HR infrastructure amid rapid company growth. In this strategic and high-profile role, you will streamline HR processes, enhance the employee lifecycle from onboarding to offboarding, and manage our HR compliance program. The ideal candidate is passionate about creating a best-in-class employee experience, has a knack for improving systems and processes, keen attention to detail and thrives in an exciting fast-paced environment. They are a data-driven operations expert with deep knowledge of HR best practices, HR systems and platforms, and are excited to scale people operations in a growing organization.

HR Operations & Systems

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  Champion, lead and optimize HR processes across the full employee lifecycle (onboarding ? offboarding)

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  Manage HR systems (PEO/HRIS, ATS, LMS, payroll), ensuring data accuracy, integrity, and compliance

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  Proactively anticipate and conduct regular HR and payroll data audits and management reporting

Employee Lifecycle & Experience

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  Lead onboarding, offboarding, and employee transitions for employees and contractors

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  Create and deliver exceptional employee support while maintaining strict confidentiality

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  Lead benefits selection and administration and other related health/welfare programs

Compliance, Data & Analytics

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  Drive HR data management including compensation analysis, equity strategies, and demographic analysis

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  Partner with Legal on facilitating visa and immigration processes

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  Ensure compliant, accurate employee records

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  Take the lead in auditing and delivering data requests working in tandem with Finance colleagues

Compensation, Performance & Development

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  Create compensation equity reviews, coordinate a total compensation strategy, and advise on organizational changes

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  Create new approaches for performance management and career development design

Cross-Functional Partnership

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  Partner with Finance, Legal, IT, and Talent Acquisition to streamline HR operations

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  Lead talent acquisitions strategies as needed, including assessment and interview coordination

On-Site- Mountain View, CA

$125K to $150K base salary

Varies depending on qualifications and experience level

Compensation includes a base salary, an annual target bonus, and an equity grant

• Bachelor’s degree and 5–8+ years of progressive People/HR Operations experience

• Prior experience in a high-growth startup environment (required)

• Experience in Biotech and/or Life Sciences (a big plus)

• Proven ability to design and scale HR processes and systems across a distributed workforce

• Strong organizational skills with exceptional attention to detail and data accuracy

• Proficiency with HRIS, ATS, LMS, payroll systems, and modern collaboration tools

• Strong analytical, problem-solving, and communication skills

• Experience managing confidential information with integrity and discretion

• Working knowledge of multi-state and federal employment laws, with California expertise preferred

• Proactive, nimble, hands-on, and results-oriented mindset

• Comfortable supporting remote teams and collaborating cross-functionally

• Strong cultural contributor with a “we-before-me” approach and commitment to continuous learning

At Alto Neuroscience, you make a difference within the company and in the world. You will play a pivotal role in advancing precision psychiatry and improving how mental health disorders are treated. Join us in building the next generation of personalized neuroscience-based therapeutics.

Alto Neuroscience is an equal-opportunity employer that does not discriminate on the basis of sex, age, race, color, religion, marital status, sexual orientation, gender identity, pregnancy, disability, or any other characteristic protected by law. We offer a welcoming and inclusive environment in service to one another, our products, the diverse consumers we represent, and the communities we call home. We do all of this with kindness, empathy and respect for each other. The above is intended to describe the general content of and requirements for the performance of this job. It should not be construed as an exhaustive statement of duties, responsibilities or physical requirements.

#LI - Onsite