LIMS Associate

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for a LIMS Associate to join our growing superstar Process Engineering team in support of clinical patient testing in our high throughput CLIA lab. The LIMS Administrator will be responsible for (1) Evolving the sophistication and usage of BTO’s LIMS tools to support rapid scaling of our clinical lab, (2) Identifying and implementing new Quality-oriented changes which enable greater usage, surveillance/monitoring, and control of laboratory data, (3) Managing a relationship with third party developers and our internal engineering team in system integration efforts, and (4) Identifying and assessing new LIMS systems which could offer greater benefits to BTO’s larger operations.

This role will help to build upon the strong technology and execution found within BTO’s walls, and will help us pave the way for replicating our prenatal success in the oncology space. The LIMS Associate is a full-time on-site position (in either our Menlo Park or Union City sites) and reports to the Associate Director of Process Engineering. 

• →Collaborate closely with wet lab scientists in our clinical molecular biology lab to understand workflows and the corresponding data flow needs
• →Perform routine LIMS systems and software maintenance procedures
• →Collaborate with SMEs to design & implement LIMS workflows & to support new assay launches
• →Work with the LIMS Administrator to manage existing LIMS workflows, their operations, lifecycle and data
• →Manage full release process, including validation, coordination of training, completion of required documentation, and deployments
• →In coordination with the LIMS Administrator, liaise with Semaphore Solutions, the external developer of the Labbit LIMS, and with other third party contractors & developers, as needed
• →Monitor, troubleshooting, and correct systems and software technical issues (e.g. resolving bugs and LIMS outages)
• →Triage & escalate unresolved technical issues to appropriate internal teams or external developers
• →Network with internal stakeholders & customers to develop new technologies
• →Develop and maintain relevant technical documentation (SOPs, Policies, etc) for use of BTO’s LIMS systems
• →Create workflow diagrams and documentation of current and proposed lab processes
• →Ensure compliance to all relevant corporate and regulatory requirements
• →Collaborate with the LIMS Administrator to provide  end-to-end support & ownership for tickets requiring system change
• →Train SMEs in Software Engineering, Data Science, and CLIA to understand LIMS API and data warehouse
• →Onboard personnel to LIMS and define systems, roles, and responsibilities
• →Assist in establishing scope of features based on goals and timelines
• →Monitor KPIs for Labbit LIMS and work with LIMS Administrator and lab personnel to ensure timely progress toward company goals

• Collaborate closely with wet lab scientists in our clinical molecular biology lab to understand workflows and the corresponding data flow needs
• Perform routine LIMS systems and software maintenance procedures
• Collaborate with SMEs to design & implement LIMS workflows & to support new assay launches
• Work with the LIMS Administrator to manage existing LIMS workflows, their operations, lifecycle and data
• Manage full release process, including validation, coordination of training, completion of required documentation, and deployments
• In coordination with the LIMS Administrator, liaise with Semaphore Solutions, the external developer of the Labbit LIMS, and with other third party contractors & developers, as needed
• Monitor, troubleshooting, and correct systems and software technical issues (e.g. resolving bugs and LIMS outages)
• Triage & escalate unresolved technical issues to appropriate internal teams or external developers
• Network with internal stakeholders & customers to develop new technologies
• Develop and maintain relevant technical documentation (SOPs, Policies, etc) for use of BTO’s LIMS systems
• Create workflow diagrams and documentation of current and proposed lab processes
• Ensure compliance to all relevant corporate and regulatory requirements
• Collaborate with the LIMS Administrator to provide  end-to-end support & ownership for tickets requiring system change
• Train SMEs in Software Engineering, Data Science, and CLIA to understand LIMS API and data warehouse
• Onboard personnel to LIMS and define systems, roles, and responsibilities
• Assist in establishing scope of features based on goals and timelines
• Monitor KPIs for Labbit LIMS and work with LIMS Administrator and lab personnel to ensure timely progress toward company goals

• Experience with Illumina NGS workflows
• Experience with molecular biology workflows in a high-throughput environment
• Experience developing scripting solutions to automation problems in a fast paced/agile setting
• Experience with automated liquid handlers and software integrations
• Familiarity with AWS S3
• Familiarity with cloud applications and with EC2
• Familiarity with structured data types, including JSON
• Experience with REST APIs 
• Experience with the Labbit LIMS platform
• Direct experience with multiple LIMS products (Clarity, STARLIMS, Labvantage, Labworks, etc)
• Familiarity with Quality Management Systems such as Arena and with related regulations (CFR 21 Part 11, ISO 13485, etc) 
• Experience with data analysis using Excel, SQL, R, and/or Python
• Experience with ticket support in a production environment
• Experience with bioinformatics pipelines

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com