Clinical Research, Project Manager
Quick Summary
Castle Biosciences Earns "Top Workplaces USA Award" for Phoenix, Pittsburgh, and Friendswood! Castle Biosciences Inc. is growing,
Castle Biosciences Earns "Top Workplaces USA Award" for Phoenix, Pittsburgh, and Friendswood!

Castle Biosciences Inc. is growing, and we are looking to hire a Clinical Research Project Manager working from our Friendswood, TX, Pittsburgh, PA, or Phoenix, AZ office locations. Remote work may also be considered for candidates located outside of the local office locations, with a start date prior to June 1, 2026.
Why Castle Biosciences?
- Exceptional Benefits Package:
- Excellent Annual Salary + Bonus Potential
- 20 Accrued PTO Days Annually
- 10 Paid Holidays
- 401K with 100% Company Match up to 6%
- 3 Health Care Plan Options + Company HSA Contribution
- Company Stock Grant Upon Hire
A DAY IN THE LIFE OF A Project Manager
This position will act as a Clinical Research, Project Manager responsible for leading feasibility planning, site engagement, and project execution for clinical trials across multiple disease states. The role bridges early trial feasibility with long-term site support and quality improvement to ensure trials are successfully launched and optimized. Key responsibilities include developing and implementing feasibility strategies to evaluate site capabilities, analyze trial designs, and recommend appropriate sites; identifying, recruiting, and onboarding participating hospitals and health systems; and providing targeted education and training to sites and stakeholders. The Project Manager will oversee protocol start-up, regulatory monitoring, and sponsor-level implementation activities, collaborating with internal teams and external partners to meet project deliverables on time while communicating progress and challenges to leadership. They will also work closely with the Clinical Trial Liaison and Study Operations teams to strengthen study center engagement, improve patient enrollment, and ensure regulatory compliance, while maintaining expertise in assigned therapeutic areas across the company's clinical portfolio.
REQUIREMENTS
- Bachelor's degree or equivalent (health sciences field preferred), or registered nursing certification.
- 3-5 years of experience in clinical research, healthcare, or public health-related programs.
- Proven experience in people management. Minimum of 1 year managing direct reports.
- Superior organizational and time management skills, ability to manage multiple concurrent tasks, determine relative importance and prioritize accordingly.
- Strong medical or clinical research background.
*Please see the full success profile at the end of the job ad.
TRAVEL/WORK ENVIRONMENT
- Located in the Friendswood, TX, Pittsburgh, PA, or Phoenix, AZ office, or remotely from a home office in a major U.S. city with access to a major airport.
- Occasional travel may be required for training or site visits; approximately 4 times per year for site visits but may be more.
SCHEDULE
- Monday through Friday, 40 hours per week, exempt position, working from the Friendswood, TX, Pittsburgh, PA, or Phoenix, AZ office locations. Remote work may also be considered for candidates located outside of the local office locations.
READY TO JOIN OUR BIOTECH TEAM?
We truly appreciate your time. If this feels like the right opportunity for you, we'd love for you to complete our mobile-friendly application. We're excited to learn more about you and look forward to connecting soon!
Castle Biosciences Awards and Research Developments!
WORK AUTHORIZATION
All candidates must be legally authorized to work in the United States. Currently, Castle Biosciences does not sponsor H-1B visas, OPT, or employment-related visas.
ABOUT CASTLE BIOSCIENCES INC.
At Castle, it all comes down to people. After all, disease doesn't just happen - it happens to people. We believe that disease management and treatment decisions can be better informed through a person's unique biology, which is revealed through the scientific rigor of our innovative, laboratory-developed tests. We are committed to empowering healthcare providers and patients with the goal of improved outcomes.
Every employee at Castle has an impact on patient care, and we work to ensure that everyone finds their work to be both challenging and rewarding. We behave with integrity and treat our colleagues with respect and kindness. Our culture fosters an environment of trust, transparency, and collaboration. We prioritize and encourage internal growth and professional development.
Castle Biosciences is an equal opportunity employer as to all protected groups, including protected veterans and individuals with disabilities.
If you have a disability and you believe you need a reasonable accommodation in order to search for a job opening or to submit an online application, please e-mail ReasonableAccommodationsRequest@castlebiosciences.com.
This email was created exclusively to assist disabled job seekers whose disability prevents them from being able to apply online. Only messages left for this purpose will be returned. Messages left for other purposes, such as following up on an application or technical issues not related to a disability, will not receive a response.
** No third-party recruiters, please
Location & Eligibility
Listing Details
- First seen
- May 22, 2026
- Last seen
- May 22, 2026
Posting Health
- Days active
- 0
- Repost count
- 0
- Trust Level
- 51%
- Scored at
- May 22, 2026
Signal breakdown
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