Director / Senior Director, US Market Access

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugate therapies. Our pipeline includes varegacestat, a late-clinical stage GSI; IM-1021, a clinical-stage ROR1 ADC; and IM-3050, a FAP-targeted radiotherapy that recently received IND clearance. We are also advancing a broad portfolio of early stage ADCs pursuing undisclosed solid tumor targets.

Immunome is seeking an experienced and strategic Director / Senior Director, US Market Access to develop and execute the US market access strategy for our oncology portfolio. This role will lead payer and channel strategy for varegacestat from pre-launch through launch, overseeing payer marketing materials, pricing, value proposition development, and contracting, while also helping shape U.S. market access strategy for pipeline assets as they advance into late-stage development.

The successful candidate will bring deep expertise in the US payer landscape and specialty access pathways, along with a proven track record executing market access plans that maximize patient access. This role will partner closely with HEOR, Distribution/Trade, and field teams to deliver coverage, pull-through, and patient access solutions.

• Develop the integrated US market access strategy for pipeline and launch products across commercial, Medicare, Medicaid, and institutional segments.
• Lead access planning and launch readiness, including payer segmentation, access objectives, and pull-through tactics.
• Track access KPIs (coverage, utilization management, time-to-therapy, net price) and drive actions to remove barriers.

• Partner with HEOR and Medical to define the value story, evidence plan, and payer value proposition.
• Lead/co-lead development of payer-facing materials (AMCP dossier, value deck, formulary submission tools, reimbursement guides).
• Support field execution through training, messaging, and tools for payer discussions and pull-through.

• Develop US pricing strategy and gross-to-net assumptions; support pricing governance and scenario modeling.
• Lead contracting strategy and execution with payers, PBMs, IDNs, and key customers; coordinate operational implementation with Legal/Compliance and Distribution/Trade.

• Collaborate with Distribution/Trade and Patient Services to define and execute on channel and distribution strategy (e.g., specialty pharmacy, specialty distributor, wholesaler).
• Support patient access services (benefit verification, prior authorization support, copay/PAP, hub operations) to reduce time-to-therapy.
• Monitor payer policy and reimbursement changes; use analytics and field feedback to proactively address access issues.

• Serve as market access lead across cross-functional teams (HEOR, Medical, Commercial/Brand, Distribution/Trade, and field).
• Provide clear access insights and recommendations to senior leaders, translating payer feedback into decisions.
• Build relationships with payers and health systems; lead payer research/advisory boards and manage external partners as needed.

• Bachelor's degree required; advanced degree (MBA, MPH, PharmD) preferred.
• Director: 7+ years in US market access/pricing/contracting or ; Senior Director: typically 9+ years with leadership experience.
• Demonstrated success developing and executing US market access strategies for specialty products; oncology preferred.
• Experience developing payer marketing deliverables (AMCP dossier, payer value deck, value proposition) with HEOR/Medical.
• Proven track record negotiating and implementing payer/customer contracts to maximize patient access.
• Experience partnering with Distribution/Trade and patient services models (specialty pharmacy, buy-and-bill, hub, copay/PAP).
• Strong influencing and communication skills; ability to thrive in a fast-paced biotech environment.

• Deep understanding of US reimbursement across Commercial, Medicare (Part D/Part B), Medicaid, and institutional segments.
• Strong knowledge of specialty access pathways, utilization management levers, and patient affordability; oncology experience strongly preferred.
• Expertise in strategic pricing, contracting structures, gross-to-net drivers, and access analytics.
• Ability to translate clinical and economic evidence into clear, compelling payer value narratives and materials.
• Demonstrated success partnering with HEOR, Distribution/Trade, and field teams to drive execution and pull-through.
• Excellent negotiation, presentation, and executive-level communication skills.
• Analytical mindset and comfort using data to track access performance and inform decisions.
• Strong project management skills and ability to manage vendors/consultants and multiple priorities.

Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish).