Staff Software Engineer, Full Stack - Early Cancer Detection (ECD)
Quick Summary
POSITION SUMMARY: We are seeking an experienced Staff Software Engineer, Backend (or Full Stack) , for our Early Cancer Detection (ECD) program, who excels at collaboratively solving complex problems.
Responsibilities
~1 min read- →
Design, develop, and maintain scalable services that support the diverse activities of a high-throughput laboratory.
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Develop back-end applications that interact with other software.
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Implement and manage CI/CD pipelines using GitLab.
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Develop comprehensive tests (unit, api, integration) to ensure high code quality.
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Collaborate closely with end-users and product managers to iterate on requirements and deliverables.
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Optimize architecture and infrastructure on the AWS cloud platform for performance, scalability, reliability, and cost-effectiveness.
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Proactively monitor system performance, troubleshoot issues, conduct thorough root cause analysis, and implement enhancements to improve efficiency and reliability.
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Stay current with emerging technologies and best practices in software engineering and actively contribute to continuous improvement initiatives.
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Be the technical lead and mentor more junior engineers.
Requirements
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BS degree in computer science, comparable program, or equivalent.
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10+ years of full stack software development experience.
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Proven experience with programming languages such as TypeScript (preferred), or Python
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Experience with software development lifecycle process from build, software configuration, change control, and release and deployment activities.
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Strong quality assurance mindset with a commitment to delivering robust and reliable software.
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Proficiency in messaging frameworks such as Kafka.
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Proficiency in infrastructure as code (IaC).
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Excellent problem-solving skills and the ability to work both independently and collaboratively in a dynamic environment.
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Excellent use of modern Agent-Driven development practices.
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Strong written and verbal communication skills, coupled with excellent interpersonal skills enabling effective interaction with stakeholders at all levels.
Nice to Have
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Experience working in highly regulated environments.
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Able to visit the lab in San Carlos, CA on a regular basis to facilitate direct observation of the software in the lab and obtain real-time user feedback.
What We Offer
~2 min readThis range reflects a good-faith estimate of the base pay we reasonably expect to offer at the time of hire. Final compensation will vary based on experience, qualifications, and internal equity considerations.
This position is also eligible for additional compensation and benefits through Natera’s robust Total Rewards program, including:
Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
Location & Eligibility
Listing Details
- Posted
- May 26, 2026
- First seen
- May 26, 2026
- Last seen
- May 27, 2026
Posting Health
- Days active
- 0
- Repost count
- 0
- Trust Level
- 79%
- Scored at
- May 26, 2026
Signal breakdown

Natera is a global leader in cell-free DNA (cfDNA) testing, specializing in reproductive health, oncology, and organ transplantation.
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