2d ago
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Senior Principal Scientist, Clinical Research, Thoracic Malignancies

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Overview

Job Description Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today,

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OtherPrincipal

Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company - one that is ready to help create a healthier future for all of us.  Our ability to excel depends on the integrity, knowledge, imagination, skill and teamwork of an individual like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you'll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career. 

The Senior Director (Sr. Principal Scientist) has primary responsibility for the planning and directing clinical research activities involving new or marketed Oncology medicines. Our Company's Oncology medicines span all phases of clinical development (pre-clinical to post-licensure). The Director will manage the entire cycle of clinical development, including: study design, placement, monitoring, analysis, regulatory reporting, and publication.

• Evaluating pre-clinical and translational work for the purpose of generating early clinical development plan and Investigational New Drug applications;

• Developing of clinical development strategies for investigational or marketed Oncology drugs

• Planning clinical trials (design, operational plans, settings) based on these clinical development strategies

• Monitoring and managing the conduct of ongoing or new clinical trials for investigational or marketed Oncology drugs;

• Analyzing and summarizing the clinical findings from studies to support decisions regarding safety and efficacy as well as new drug applications, clinical study reports, or publication; and

• Participation in internal and joint internal/external research project teams relevant to the development of new compounds, and the further study of marketed compounds. In executing these duties, the

• Supervise the activities of Clinical Scientists in the execution of clinical studies

• Work closely with a cross-functional group of experts in commercialization, regulatory affairs, statistics, and manufacturing to manage clinical development projects; and

• Assist the Senior/Executive Director in ensuring that appropriate corporate personnel are informed of the progress of studies of our Company's and competitors' drugs and internal and external expert opinion on scientific questions relevant to his/her areas of responsibility.

• Maintaining awareness of scientific developments within his/her area of expertise, in terms of new scientific findings, research methodologies

• Identification of scientifically and operationally strong investigators who can assist in the development of our Company's investigational and marketed drugs

• Establishing communications with prominent clinical investigators in his/her particular field of interest, particularly those who will be willing and able to assist in the evaluation of our Company drugs

• Attending appropriate scientific meetings to maintain his or her competency and to maintain awareness of research activities in his/her area of responsibility.

• Author detailed development documents, presentations, budgets, and position papers for internal and external audiences

• Facilitating collaborations with external researchers around the world

• Travel on company business about twenty (20) percent of the time to manage future or ongoing clinical research projects.

Requirements

~1 min read

Regular

25%

• M.D or M.D./Ph.D.

• Must have experience in industry or senior faculty in academia

• Minimum of 3 years of clinical medicine experience

• Minimum of 3 year of industry experience in drug development or biomedical research experience in academia

• Demonstrated record of scientific scholarship and achievement

• A proven track record in clinical medicine and background in biomedical research is essential

• Strong interpersonal skills, as well as the ability to function in a team environment are essential.

• Outstanding verbal and written communication and presentation skills

Nice to Have

~1 min read

• Board Certified or Eligible in Oncology

• Prior specific experience in clinical research and prior publication

Current Employees apply HERE

Current Contingent Workers apply HERE

Cancer Research, Clinical Development, Clinical Trials, Cross-Functional Teamwork, Drug Development, Oncology Trials

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.  As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement​

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The salary range for this role is

$282,200.00 - $444,200.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits.  Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

Domestic

Yes

Hybrid

Not Indicated

No

n/a

10/15/2026

Location & Eligibility

Where is the job
—
Location terms not specified
Who can apply
Same as job location

Listing Details

Posted
September 30, 2026
First seen
October 1, 2026
Last seen
October 1, 2026

Posting Health

Days active
0
Repost count
0
Trust Level
49%
Scored at
October 2, 2026

Signal breakdown

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Senior Principal Scientist, Clinical Research, Thoracic Malignancies