Principal Technology Strategist, Lab Systems

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  Design the architectural framework for next-generation sample accessioning and triage, utilizing automation and intelligent routing to minimize manual data entry and sample handling errors.

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  Define the strategy for End-to-End Workflow Tracking, ensuring real-time visibility of sample status from kit activation through wet-lab processing to final clinical reporting.

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  Lead the modernization of Workflow Orchestration, moving away from static, hard-coded paths toward a dynamic, metadata-driven engine that supports complex branching across multiple lab sites.

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  Partner with Lab Ops to identify "automation-first" opportunities, ensuring software and robotics (Hamilton, Tecan, etc.) are deeply integrated for maximum throughput.

• Architect the "Digital Bridge" between Laboratory Information Systems (LIMS) and commercial platforms, ensuring robust, bi-directional data flow with EMR/EHR systems and Provider Portals.

• Collaborate with Customer Experience (CX) teams to ensure lab data is surfaced to patients and providers through modern, API-driven interfaces.

• Lead the technical strategy for "Order Triage," ensuring complex clinical orders are validated and routed correctly across diverse business units (Oncology, MRD, WH).

• Lead deep-dive technical evaluations of third-party LIMS, Middleware, and RCM integration engines, weighing them against the long-term benefits of our homegrown informatics ecosystem.

• Develop the technical roadmap for transitioning legacy, siloed databases into a unified enterprise data fabric that supports both clinical operations and downstream R&D.

• Act as the lead technical advisor to the SVP and a mentor to the 400-person engineering organization, fostering a culture of "Systems Thinking."

• Bridge the gap between the "Physical Lab" and "Digital Software," ensuring that architectural decisions account for the realities of clinical scale and regulatory rigor (CLIA/CAP/FDA).

• 10+ years of experience in enterprise software architecture, with a heavy emphasis on Laboratory Informatics, LIMS, or Healthcare IT.

• Demonstrated success designing systems that manage high-volume sample lifecycles (Accessioning, Triage, and Orchestration).

• Proven expertise in Enterprise Integration Patterns, specifically connecting clinical lab systems to EMRs and RCM/Billing platforms.

• Deep understanding of the "Order-to-Cash" technical journey in a diagnostic or medical device environment.

• Strong executive presence with the ability to influence Lab Operations, Commercial, and Engineering stakeholders.

• Familiarity with FDA-regulated software and Computer System Validation (CSV) for complex integrations.

• Background in Genomics or Oncology, specifically handling the complexities of "Dry Lab" data pipelines and "Wet Lab" physical constraints.

This is a remote role requiring periodic travel to San Carlos, CA and Austin, TX. On-site "floor time" in the clinical labs is essential to understand the operational challenges this role is tasked with solving.

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.