General Manager, Thesis

United StatesNew Yorkmid
OtherGeneral ManagerAnnuities General Manager
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Overview

About Us The human brain is the most complex object in the universe, yet society has accepted one-size-fits all approaches to cognition. The "solutions" (think coffee, energy drinks,

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OtherGeneral ManagerAnnuities General Manager

The human brain is the most complex object in the universe, yet society has accepted one-size-fits all approaches to cognition. The "solutions" (think coffee, energy drinks, and even a friend's rx) were mediocre at best and frankly, made no sense to us. So, we created Thesis, the world's first customized nootropics company. If you've never heard that word before, it's just a fancy way of saying brain supplements. In five years, most will be taking nootropics on the daily and chances are, they'll be ours.

With an exceptional efficacy rate, the world has taken notice — we've raised over $13M in venture capital, garnered interest from leading neuroscientists and athletes, and established ourselves as the industry's leading brand. Now, we're looking for incredible people to help us share the gift of enhanced cognitive function with the world. If you're looking to be a part of a movement — one that involves both immense self-growth and an ambitious mission to pioneer an industry — we'd love to have you on the team.

About the Role

~1 min read

As the General Manager of Thesis, you will play a pivotal role in scaling the world's leading personalized nootropics brand. You will be responsible for developing strategic plans, driving P&L performance, and executing growth initiatives across our omnichannel business. Your expertise in P&L ownership, marketing leadership, strategic planning, and cross-functional collaboration will be instrumental in achieving our ambitious growth goals. Working closely with the CEO and leadership team, you will drive roadmap execution, establish operational KPIs, and position Thesis for continued category leadership. Your ability to operate strategically while executing tactically will be crucial in accelerating our mission to bring personalized cognitive enhancement to millions.

  • Bachelor's or Master's degree in Business, Marketing, or related field; MBA strongly preferred.

  • 10+ years of overall work experience including experience in a GM, growth, or operations role at a high-growth company.

  • Demonstrated ability to navigate both established corporate environments and agile startup dynamics.

  • Previous experience in health/wellness, CPG, and/or DTC e-commerce as a brand manager, product manager, or general manager.

  • Proven success in owning a P&L and driving business unit KPIs in a growth-stage environment.

  • Strong analytical skills, with demonstrated ability to build both tactical budgets and long-term strategic growth plans.

  • Experience managing brand evolution from early-stage through scaling, ideally in personalized or science-backed products.

  • Strong project management skills with ability to manage multiple priorities and drive consensus across stakeholders.

  • Previous startup experience strongly preferred; experience in venture-backed companies a plus.

  • Passion for cognitive enhancement, neuroscience, or related fields that drive our mission.

What We Offer

~1 min read
💵 Competitive compensation with an exceptionally generous equity package
🩺 Competitive Health, dental, and vision plans (including a 100% covered premium plan for all 3!)
🚆 HSA, FSA and pre-tax commuter benefits for parking and transit
🚀 Ancillary benefits through Talkspace, One Medical, Kindbody, Teladoc, Classpass and more!
📈 401k to help you plan for the future
🏖 Flexible PTO because we respect the need for work/life harmony
🏋 $100 monthly wellness stipend for your wellbeing (e.g. massage, cryotherapy, psychedelic therapy, etc.)
💊 Unlimited (yes, unlimited) Thesis nootropics
🎓 A strong emphasis on promoting from within and personal development
🐕 A dog-friendly office located in the heart of Flatiron steps from Union Square and Madison Square Park
🏢 Hybrid work model
  • Meet Your Potential: At Thesis, we create opportunities for personal and professional growth. We reward hard work, dedication, and an entrepreneurial spirit. We believe in open and honest feedback to help us continually learn and improve. In return, we are committed to providing the resources, support, and guidance for our team to achieve their ambitions and meet their potential.

  • Own Outcomes: We are driven by achieving meaningful results, both for our customers and our business. We're proactive, conscientious, and take responsibility equally in times of triumph and challenge. We also operate with a sense of urgency because we want to seize the opportunity to create a new category and bring nootropics to everyone who needs them.

  • Lead with Science and Data: We are obsessed with data to understand our impact, and always seek the truth through objective metrics that help us make informed decisions. Science and evidence underpin everything we do, from product formulation to marketing claims. We're committed to making the highest quality nootropics on the market and measuring our efficacy.

  • Create Exceptional Experiences: We are committed to creating a work environment that fosters a unique culture and deep sense of belonging. We create exceptional experiences by showing up for each other, giving each other the benefit of the doubt, and building an inclusive and warm environment—in and outside of the office. We're equally committed to showing up for our customers by delivering a thoughtful and impactful experience for anyone who tries one of our products.

Listing Details

Posted
February 10, 2026
First seen
March 26, 2026
Last seen
April 22, 2026

Posting Health

Days active
26
Repost count
0
Trust Level
23%
Scored at
April 22, 2026

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General Manager, Thesis