Associate Scientist

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The Department of Cell and Systems Biology has an exciting opportunity for a full-time Associate Scientist to work on-site in Miami, FL.

The Associate Scientist will be involved in building next-generation models of human cell biology relevant to regeneration and disease. They will establish a cohort of patient-derived and gene edited cell lines for "in vitro clinical trials" related to cell biological disorders such as polycystic kidney disease and cystinosis, characterizing these cell lines and derived organoids, and applying these tools to investigate mechanisms of disease and candidate therapeutics. Additional models such as mouse or human datasets will also be analyzed as comparators, and animal work may be conducted as an additional research area. The Associate Scientist will contribute meaningfully to grant applications, manuscripts, and will have the opportunity to mentor junior scientists. They will also take on part-time lab management duties, including acting as a chemical hygiene officer for the laboratory, assisting with ordering issues, interacting with various agencies and safety departments, writing risk assessments and SOPs, overseeing common lab databases and inventories, and delegating lab tasks to individual lab members. They will also help interface with the Division, approve orders and time sheets (if possible), aliquot and distribute key common reagents, work with vendors to secure competitive prices, help prepare IACUC submissions, maintain equipment or surplus, and help schedule team building and recognition exercises.

1. Cell culture – daily differentiation and maintenance of human pluripotent stem cells or cell lines

2. Microscopy – immunofluorescence, confocal, wide-field, live cell

3. Genome editing – guide RNA construction, transfection, screening

4. Drug discovery – design and execution of assays to test therapeutic candidates

5. Drug development – hit-to-lead advancement, preclinical workup (pharmacokinetics/metabolism)

6. Biochemistry and molecular biology – qPCR, electrophoresis, immunoblotting, cloning

7. Computing and analysis – Illustrator, PowerPoint, Excel, Word, ImageJ, HTML, GraphPad

8. Documentation – daily record of work performed in files and laboratory notebook

9. Contribute data and ideas for reports and publications

10. Assist in seeking/acquiring additional funding

11. Prepare summary slides and presentations of projects to share with stakeholders

12. Figure and text preparation for peer-reviewed manuscripts

13. Manage junior lab members

14. Lead projects or project tasks toward research objectives

15. Inventory management for reagents/orders/cells

16. Track orders and expenses

17. Ensure compliance with lab regulations and completion of corresponding paperwork

18. Aid PI in communications with administrative staff and scientific collaborators

This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.

Doctorate degree - Philosophy (PhD) required

Refer to department description for applicable certification requirements

Minimum 5 years of relevant experience required

• Learning Agility: Ability to learn new procedures, technologies, and protocols, and adapt to changing priorities and work demands.
• Teamwork: Ability to work collaboratively with others and contribute to a team environment
• Technical Proficiency: Skilled in using office software, technology, and relevant computer applications. - Communication: Strong and clear written and verbal communication skills for interacting with colleagues and stakeholders.

The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

The University of Miami is an Equal Opportunity Employer. Applicants and employees are protected from discrimination based on certain categories protected by Federal law.