Associate Sequencing Scientist (WA)

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Quick Summary

Overview

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Key Responsibilities

Oversees the design, development, evaluation, and implementation of NGS assays, including amplicon-based sequencing and whole genome sequencing, for the internal drug discovery pipeline.

Requirements Summary

Bachelor’s degree in Biology, Microbiology, Genetics, or a related field with 5+ years of research experience in a relevant laboratory setting, or a Master’s degree with 3+ years of relevant experience.

Technical Tools

data-analysis

Responsibilities:

Oversees the design, development, evaluation, and implementation of NGS assays, including amplicon-based sequencing and whole genome sequencing, for the internal drug discovery pipeline.
Conducts independent laboratory research to develop and apply advanced NGS techniques and methodologies.
Engages in scientific literature analysis to identify methodological gaps, designing protocols and contributing to experimental plans for developing new sequencing strategies to meet business needs.
Collaborates with the internal data analysis team to create methods for analyzing NGS data, incorporating cutting-edge NGS technologies.
Manages long-read and single-molecule sequencing, including library preparation, instrument operation, and maintenance.
Troubleshoots and evaluates prepared libraries, addresses data quality issues, and resolves sequencing instrument concerns.
Extracts high molecular weight DNA and high-quality RNA from a variety of biological samples.
Coordinates across teams to ensure timely and efficient delivery of high-quality results.
Functions effectively both independently and as part of a team to resolve protocol challenges and deliver results.
Follows and reviews standard operating procedures to ensure reproducibility.
Collaborates with colleagues to troubleshoot equipment and optimize processes.
Prepares and presents experimental data to cross-functional teams.

Qualifications:

Bachelor’s degree in Biology, Microbiology, Genetics, or a related field with 5+ years of research experience in a relevant laboratory setting, or a Master’s degree with 3+ years of relevant experience.
Proficient in molecular biology techniques, including DNA construct design, PCR, qPCR, RT-PCR, molecular cloning, plasmid extraction, and DNA sequencing.
Experience with Illumina NGS technology.
Experience with PacBio technology is a plus.
Knowledge of various DNA cloning methods, such as Gibson and Golden Gate assembly techniques, along with bacterial strain engineering, is an advantage.

This is a full time position

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