Kcasbio14d ago

Associate Scientist - Mass Spec Development (LC-MS/MS)

Kansas CityRegular - Full Timemid

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Overview

Performing critical work that impacts our industry and our world’s health while problem solving and innovating in the field – that is what Associate Scientists at KCAS Bio get to do every day.

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Performing critical work that impacts our industry and our world’s health while problem solving and innovating in the field – that is what Associate Scientists at KCAS Bio get to do every day. If that gets you excited too, then maybe working as an Associate Scientist at KCAS Bio is the role for you.

When you work as an Associate Scientist in the Mass Spec Bioanalysis Development group at KCAS, you get to further our mission by applying your knowledge in bioanalytical and scientific principles to support study execution and development activities with increasing independence. You will contribute to study activities from setup through data generation while continuing to build your ability to assess data integrity and troubleshoot with guidance.

Our Mass Spec Bioanalysis Development team uses LCMS (Liquid Chromatography Mass Spectrometry) techniques to conduct sophisticated sample preparation to meet bioanalytical needs for drug discovery, preclinical, and clinical studies, including bioanalysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues.

Execute assigned study activities including sample preparation (extractions, enrichments/affinity capture, digestions) and LCMS analysis with moderate supervision

Support method development and qualification activities and begin contributing to optimization efforts

Perform data processing and prepare data summaries for review by senior scientists

Troubleshoot routine technical issues and escalate more complex challenges appropriately

Maintain accurate documentation in compliance with study protocols, SOPs & regulatory requirements

Ensure proper sample identification, handling, and tracking

Communicate progress and risks to senior staff

Perform all aspects of the job in a way that supports company brand and supports company mission, vision, and values

Bachelor’s or master’s in chemistry, Biochemistry or chemical/biochemical engineering, or related field with 1–3 years of experience with LC-MS/MS

Hands-on experience with bioanalytical sample preparation and quantitative LC-MS/MS techniques

Working knowledge of chromatographic principles and mass spectrometry

Experience with small molecule analysis; exposure to proteins, peptides, or biomarkers is a plus

Familiarity with laboratory documentation and working in a structured or regulated environment preferred