Bioinformatics Associate, Oncology

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for a Bioinformatics Associate, Oncology to join our growing bioinformatics team. The bioinformatics team is responsible for analysis and pipeline development for our Northstar oncology products. Our sample volume is growing extremely quickly. As a Bioinformatics Associate, you will be working with a team of talented bioinformaticians to scale up our analysis pipeline to analyze tens of thousands of samples. The Bioinformatics Associate role is a full-time onsite position in Menlo Park, CA and reports to the Sr. Manager of Bioinformatics, Oncology.

• →Perform analysis of clinical bioinformatics data while maintaining low turnaround time for data delivery
• →Maintain and develop sophisticated and robust next-generation sequencing analysis pipeline
• →Collaborate with other teams from CLIA lab, Software Engineering, Quality Assurance, and R&D to improve and scale our clinical workflows

• BS or MS in Bioinformatics, Computational Biology, Computer Science, Bioengineering, Physics or related field
• Very strong programming skills in Python
• Comfortable working in UNIX command-line environments
• Experience deploying code in HPC or cloud computing environments
• Strong communication skills
• Great attention to detail
• Can work in the United States without immediate sponsorship (For applicants on student visas, post-graduation OPT is acceptable)

• 2 years of research or industry experience in biotechnology
• Experience with software development in industry and ideally in a regulated environment
• Experience with Molecular biology lab techniques (DNA purification, PCR, electrophoresis) or next-generation sequencing library preparation
• Experience leading cross-functional projects involving teams of diverse backgrounds

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com