Executive Director / Senior Director, Project Management Lead

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, drawing on leadership that previously played key roles in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugate therapies. Our pipeline includes varegacestat, a late-clinical stage GSI; IM-1021, a clinical-stage ROR1 ADC; and IM-3050, a FAP-targeted radiotherapy that recently received IND clearance. We are also advancing a broad portfolio of early stage ADCs pursuing undisclosed solid tumor targets.

Position Overview 

The Executive Director / Senior Director, Project Management Lead is responsible for leading and developing Immunome’s Project Management function and ensuring consistent, high-quality project management support across Research and Development programs and functional teams. This role focuses on strengthening alignment, transparency, and execution discipline across cross-functional and program teams, while establishing scalable project management standards, governance practices, and enterprise tools.  

The Executive Director / Senior Director will oversee the project management team, ensure consistent application of planning and reporting frameworks, and partner closely with functional and program leadership to drive operational cohesion across the organization. This role will also lead Immunome’s Smartsheet platform strategy to ensure standardized communication, reporting, and project visibility across programs and functions.  

This role is ideal for a seasoned project management leader who excels at building high-performing teams, driving consistency across diverse functions, and leveraging enterprise tools to enhance transparency and execution discipline. The Executive Director / Senior Director, Project Management Lead will be instrumental in ensuring Immunome’s programs and functional initiatives are supported by standardized, scalable, and aligned project management practices.  

This position reports to the Senior Vice President of Project and Program Management and plays a key role in reinforcing organizational alignment and execution excellence.  

Responsibilities 

Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish).