Sr Scientist - Mass Spec Bioanalysis Production (LC-MS/MS)

As a Senior Scientist at KCAS Bio, you will serve as a lead technical contributor on complex bioanalytical studies, with the ability to independently execute and/or oversee all phases from study setup through final reporting, including method development and validation.

Leveraging a strong foundation in scientific principles, you will evaluate data quality, troubleshoot complex technical challenges, and ensure compliance with applicable regulatory standards.

In this role, you will act as a trusted internal expert, contributing to the advancement of scientific quality and operational efficiency while mentoring and developing less experienced scientific staff.

• Serve as lead scientist on complex studies, independently designing, executing, and troubleshooting bioanalytical methods and workflows.
• Demonstrated experience as PI on complex or high-visibility programs, including multi-analyte, multi-matrix, or global studies
• Experience supporting regulatory submissions (IND, NDA, BLA) with bioanalytical data as acting PI or key contributor
• Develop, optimize, and validate analytical methods to support drug discovery and development programs.
• Provide advanced troubleshooting support for method performance, instrumentation, and study execution issues.
• Author and review validation protocols, study plans, reports, and investigations in accordance with regulatory and quality standards.
• Provide scientific and technical support for sponsor interactions, contributing data interpretation and study rationale as needed.
• Develop and maintain SOPs and provide guidance on analytical procedures.
• Stay current with evolving scientific methodologies, instrumentation, and industry trends; apply knowledge to improve study quality and operational efficiency.
• Mentor Scientists and junior staff through hands-on training, technical guidance, and knowledge sharing.
• Perform all duties in alignment with company mission, values, and quality expectations.

• Bachelor’s degree in a scientific discipline (advanced degree preferred).
• 10–12+ years of relevant experience in research, CRO, or pharmaceutical environment.
• Expert knowledge of applicable laboratory techniques and instrumentation.
• Strong understanding of regulatory requirements and quality systems.
• Strong attention to detail and commitment to scientific excellence.
• Effective written and verbal communication skills.
• Strong technical writing and basic computer proficiency.
• Willingness and ability to mentor and coach others.
• Ability to function as a senior individual contributor and scientific role model.